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January 04, 2022
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Study: Anemia associated with complications, non-home discharge, readmission after TKA

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According to published results, preoperative anemia was associated with an increased risk for complications, non-home discharge and unplanned readmission in patients who underwent total knee arthroplasty.

Alexander L. Neuwirth, MD, and colleagues from Columbia University used the National Surgical Quality Improvement Program database to analyze data on 198,233 patients who underwent primary TKA between 2006 and 2016. Patients were separated into cohorts based on preoperative hemoglobin levels. Additionally, the researchers evaluated 30-day complication rates, readmission rates and non-home discharge rates.

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“Surgeons should attempt to identify patients with preoperative anemia and correct underlying low blood levels to help minimize the rate of postoperative complications.” Data were derived from Neuwirth AL, et al. Orthopedics. 2022;doi:10.3928/01477447-20211227-06.

After performing bivariate and multivariate analysis, Neuwirth and colleagues found patients with preoperative anemia were at a higher risk for all negative outcome measures compared with patients without preoperative anemia. Patients with anemia had a 4.73% all-complication rate, while patients without anemia had a 3.22% rate; patients with anemia had a 37% non-home discharge rate, while patients without anemia had a 24.2% rate; and patients with anemia had a 4.99% unplanned readmission rate, while patients without anemia had a 3.14% rate.

“Meticulous optimization of patients at risk for complications is critical in the era of bundled care and increased focus on rapid transition from inpatient to outpatient care,” the researchers wrote in the study. “Surgeons should attempt to identify patients with preoperative anemia and correct underlying low blood levels to help minimize the rate of postoperative complications.”