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March 24, 2025
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VIDEO: PACE remodels corneas with keratoconus without removing tissue

ATHENS, Greece — In this Healio Video Perspective from the ESCRS winter meeting, Farhad Hafezi, MD, PhD, discusses his PACE technique for keratoconus.

PACE, short for PTK-assisted customized epithelium-on cross-linking, is “customized cross-linking of the second generation.”

A special protocol for epi-on CXL stiffens the cornea as effectively as epithelium-off and is followed by customized PTK over the tip of the cone.

“In some instances, we see a massive improvement in the regularity of the astigmatism, and that translates into better vision,” Hafezi said. “The whole effect comes from cross-linking. It’s not an excimer laser effect like the Athens protocol or the Cretan protocol.”