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May 29, 2024
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VIDEO: IOP remains stable up to 48 weeks with aflibercept 8 mg for DME

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SEATTLE — In this Healio Video Perspective from the ARVO meeting, Mark R. Barakat, MD, discusses post hoc findings on IOP in patients receiving aflibercept 8 mg for diabetic macular edema in the PHOTON trial.

The analysis looked at IOP in patients who received aflibercept 8 mg in a volume of 0.07 mL vs. aflibercept 2 mg in a volume of 0.05 mL, with no significant differences found in IOP between the groups out to week 48.

“This is very encouraging that the safety profile of the 8 mg dose is very similar to the 2 mg dose, and so far, there are no signals in terms of IOP,” Barakat said.