Diabetic Macular Edema Video Perspectives

Rishi P. Singh, MD

Singh reports consulting for Alcon, Apellis, Genentech, Novartis and Regeneron.
February 01, 2023
1 min watch
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VIDEO: Treatments in the pipeline for DME

Transcript

Editor’s note: This is a previously posted video, and the below is an automatically generated transcript to be used for informational purposes. Please notify editor@healio.com if there are concerns regarding accuracy of the transcription.

The most interesting ones to me are probably the tyrosine kinase inhibitors, that seems to be closest to potential fruition as far as determining whether it's really gonna work or not. The results from some of their initial studies in both the DAVIO study and others have shown an increased durability of the treatments, in that for some patients going even six months and beyond without receiving a supplemental anti-VEGF therapy treatment. That's pretty much unheard of even with the current anti-VEGF that are available. That drug class seems the most interesting. There's also oral agents that are being tried, working on different mechanism action which have an ability to prevent the progression of diabetic macular edema, in an oral form. Again, better than injections, better than potentially drops which require you to take those daily. So again, an opportunity to possibly improve that in that category as well.