Neurology News

IV administration of fasudil at two separate doses was safe and well tolerated in a small cohort of individuals with suspected or confirmed ALS, according to new research published in The Lancet.

Pregabalin and topiramate significantly reduced the frequency and intensity of migraines in children and adolescents, especially when combined with vitamin supplements, according to a meta-analysis published in JAMA Network Open.

Biogen Inc. and Neomorph Inc. have announced a partnership geared toward research and development of molecular glue degraders to address protein accumulation related to Alzheimer’s disease and other neurologic conditions.

Top-line results of a phase 2 clinical trial for an adiposederived autologous mesenchymal stem cell therapy to address mild to moderate relapsing-remitting MS found the treatment improved mental and physical health at 52 weeks.

Plasma pTau181 in combination with ApoE4 assays registered a high degree of accuracy in ruling out patients with a low probability of amyloid pathology in the early stages of Alzheimer’s disease, according to a poster presentation at CTAD.

The International Working Group has updated diagnostic guidelines for Alzheimer’s disease to include individuals with normal cognition who test positive for core biomarkers indicative of disease pathology.

In pregnant women with MS given ocrelizumab, treatment did not result in infant B-cell depletion after birth, and the drug was virtually undetectable in the bloodstream of mother and child, according to a poster from ECTRIMS 2024.

The addition of veliparib to adjuvant temozolomide failed to improve OS for patients with newly diagnosed, MGMT-hypermethylated glioblastoma, according to randomized phase 2/phase3 study results.

On Nov. 3, most of the United States will “fall back” by an hour in the shift from daylight saving time to standard time, which will last through the winter months.

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