Pediatric Neurology News

Adolescents with migraine who have later school start times have fewer migraines, according to research published in Headache: The Journal of Head and Face Pain.

Preventive treatment with vigabatrin effectively altered the natural history of seizures among infants with tuberous sclerosis complex, decreasing the risk for and severity of epilepsy, according to results published in Annals of Neurology.

The FDA expanded its approval of lacosamide to include adjunctive therapy for primary generalized tonic-clonic seizures as well as an IV formulation for patients aged 4 years and older, according a press release.

The FDA granted orphan drug designation to AMX0035, an investigational neuroprotective therapy, for Wolfram syndrome, a rare neurodegenerative disease that causes severe neurological disabilities and results in premature death.

Treatment with vamorolone, an anti-inflammatory steroidal drug, improved motor outcomes in boys with Duchenne muscular dystrophy compared with corticosteroid-naive individuals, according to findings published in PLoS Medicine.

By some estimates, 52% of youths may experience insomnia symptoms at some point during their childhood. However, there are “notable limitations” in the current medical literature, experts wrote in Sleep.

Earlier age at disease onset and the presence of motor symptoms at disease onset predicted more rapid progression in patients with metachromatic leukodystrophy, according to study findings published in Neurology.

Use of the antiepileptic valproate during pregnancy was associated with an increased risk for neurodevelopmental disorders in offspring during early childhood, according to research published in Scientific Reports.

Child neurologists and neurodevelopmentalists do not make the diagnosis of cerebral palsy for most children with the condition, according to results of a survey of these providers that was published in Neurology.

In this video from the Annual Meeting of the American Neurological Association, Conrad "Chris" Weihl, MD, PhD, discusses the plenary session he co-chaired on the genomics of personalized medicine.