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Neuro-Oncology News
‘We were shocked’: CAR-T rapidly reduces size of brain tumors in phase 1 trial
A novel bivalent-targeting, intrathecally delivered chimeric antigen receptor T-cell therapy decreased tumor size in patients with recurrent glioblastoma, according to results from a phase 1 study published in Nature Medicine.
Most U.S. cancer trials conducted in more affluent, less diverse areas
Most of the major cancer clinical trial centers in the U.S. are located near more affluent and white populations compared with the national average, according to results published in JAMA Oncology.
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Microbubble-enhanced sonobiopsy could ‘revolutionize’ treatment of brain tumors
Focused ultrasound could provide clinicians a safer alternative in diagnosing, monitoring and treating patients with brain tumors compared with biopsy, according to findings published in npj Precision Oncology.
Multi-engineered CAR-T confers significant, rapid reduction of aggressive brain tumor
A novel chimeric antigen receptor T-cell therapy produced significant tumor reductions in patients with glioblastoma, results from a phase 1 trial published in The New England Journal of Medicine showed.
Radiation oncologist calls on field to ‘advocate and educate’ as numbers fall
Arya Amini, MD, still remembers sitting on the steps outside of his dean’s office at University of California, Irvine, more than a decade ago, prepared to race inside in case he did not get matched with a radiation oncology residency.
COVID-19 caused ‘substantial deficit’ of cancer diagnoses in first 10 months of pandemic
More than 130,000 cancer cases went undiagnosed during the first 10 months of the COVID-19 pandemic, researchers estimated in a cross-sectional analysis published in JAMA Oncology.
Traumatic brain injury, brain cancer linked in post 9/11 US military veterans
In a cohort of post-9/11 United States military veterans, moderate, severe and penetrating traumatic brain injuries were associated with the subsequent development of brain cancer, according to research from JAMA Network Open.
Expanding clinical trial diversity requires ‘showing up’ in the community to build trust
Limiting eligibility criteria, recruiting trusted community messengers and reducing financial burdens can help improve diversity of clinical trial enrollees, a panel of professionals said during a Friends of Cancer Research webinar.
Ableism in cancer care a prevalent, often overlooked health disparity
As the broader health care field strives to identify and address health care disparities, a commentary published in The Lancet Oncology underscored the importance of eliminating ableism from cancer care.
Uninsured U.S. cancer cases decline despite ‘alarming’ lack of coverage in some states
The proportion of individuals with newly diagnosed cancer who lacked insurance in the U.S. declined significantly from 2010 to 2019, according to data published in Health Affairs Scholar.
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