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February 05, 2025
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VIDEO: Inotuzumab study for acute lymphoblastic leukemia requires redesign

SAN DIEGO — Marlise R. Luskin, MD, MSCE, speaks with Healio about findings from the phase 3 randomized Alliance A041501 trial.

The study was put on hold due to grade 5 events among patients who received inotuzumab (Besponsa, Pfizer) and progressed onto chemotherapy, according to the abstract.

“On the other hand, I do think there are reasons to be encouraged by the study,” Luskin, a member of the adult leukemia program at Dana-Farber Cancer Institute and an associate professor of medicine at Harvard Medical School, said.

Reference:

  • DeAngelo DJ, et al. Abstract 308. Presented at: ASH Annual Meeting and Exhibition; Dec. 7-10, 2024; San Diego.