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December 23, 2024
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VIDEO: Major response rate for revumenib in KMT2A acute leukemia

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      In this video, Daniel DeAngelo, MD, PhD, discusses the results of a study presented at ASH Annual Meeting 2024 that examined the use of menin inhibitors in patients with leukemia.

      DeAngelo, chief of the division of leukemia at Dana-Farber Cancer Institute, highlighted a phase 2 study of revumenib (Revuforj, Syndax Pharmaceuticals) in patients with relapsed or refractory KMT2A acute leukemia.

      “These are really exciting results with single-agent therapy. It represents a new field that’s being developed with lots of players — not just revumenib, but also other menin inhibitors now are in development,” DeAngelo said.

      Reference:

      • Aldoss I, et al. Abstract 211. Presented at: ASH Annual Meeting and Exposition; Dec. 7-10, 2024; San Diego.