Childhood Cancer Awareness Month: Genetic vulnerabilities, heart health and sleep concerns
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September is Childhood Cancer Awareness Month.
The campaign is intended to spotlight the types of cancer that largely affect children, draw attention to survivorship issues, and raise funds for research and family support.
In conjunction with this observance, Healio presents the following updates in pediatric oncology that may be important to your practice.
1. A low-dose regimen of the blood pressure medication carvedilol effectively and safely improved heart health of childhood cancer survivors. Read more.
2. Incidence of pediatric cancer in the United States increased 0.5% annually on average between 2003 and 2019, according to a CDC study. Read more.
3. Survivors of childhood cancer exhibited increased risk for sleep concerns up to 30 years after diagnosis compared with cancer-free siblings. Read more.
4. Survivors of high-risk neuroblastoma face a substantial burden of late toxicity. Prevalence of some late effects varied by treatment received. Read more.
5. A functional precision medicine-guided approach appeared to increase PFS among a small cohort of pediatric patients with recurrent and/or refractory solid and hematologic cancers. Read more.
6. A partnership between health care systems along the U.S.-Mexico border led to clinically meaningful improvement in survival outcomes among children with acute lymphoblastic leukemia. Read more.
7. Bereaved parents prioritized satisfactory symptom management above all other aspects of end-of-life care for their children who died of cancer. Read more.
8. A collaboration involving Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute and St. Jude Children’s Research Hospital is designed to identify and exploit genetic vulnerabilities in pediatric cancers in order to develop better treatments. Read more.
9. Children with acute lymphoblastic leukemia receiving maintenance therapy who lived in extreme poverty had nearly double the risk for relapse compared with children who did not live in extreme poverty. Read more.
10. Despite increased interest in use of medical cannabis to alleviate cancer symptoms, there is limited rigorous evidence about the efficacy and safety of these products for pediatric patients, a systematic review and meta-analysis showed. Read more.
11. Cincinnati Children’s Hospital Medical Center has been ranked the No. 1 children’s hospital for cancer in the country. The institution tops U.S. News & World Report’s list of best hospitals for pediatric cancer for 2023-2024. Read more.
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