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Acute Lymphoblastic Leukaemia

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February 06, 2024
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BLOG: ALL relapse prevention with HSCT after CD19 CAR T-cell therapy remission

Allogeneic hematopoietic stem cell transplantation after CD19 chimeric antigen receptor T-cell therapy is thought to improve leukemia-free survival.

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September 16, 2023
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Childhood Cancer Awareness Month: Genetic vulnerabilities, heart health and sleep concerns

September is Childhood Cancer Awareness Month.

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July 11, 2023
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Overweight, obesity linked to adverse outcomes among AYAs treated for leukemia

Adolescents and young adults with overweight or obesity had poorer clinical outcomes than their normal-weight counterparts after receiving a pediatric regimen for treatment of acute lymphoblastic leukemia, study results showed.

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June 30, 2023
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FDA news: Breast cancer, sickle cell disease therapies receive priority review

The FDA announced several regulatory actions the past few weeks.

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May 25, 2023
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Cross-border partnership takes on ‘huge survival gap’ among children with leukemia

A partnership between health care systems along the U.S.-Mexico border led to clinically meaningful improvement in survival outcomes among children with acute lymphoblastic leukemia, study results showed.

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April 19, 2023
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Extreme poverty linked to nearly twofold higher risk for relapse among children with ALL

Children with acute lymphoblastic leukemia receiving maintenance therapy who lived in extreme poverty had nearly double the risk for relapse compared with children who did not live in extreme poverty, according to data published in Blood.

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February 09, 2023
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Tecartus CAR-T shows long-term durability among adults with advanced B-cell ALL

Brexucabtagene autoleucel continued to confer a greater than 70% complete remission rate among adults with relapsed or refractory B-cell acute lymphoblastic leukemia, results from the latest analysis of a pivotal phase 2 study showed.

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December 24, 2022
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ASH recap: New regimens for blood cancers; gene therapy equitable for sickle cell disease

This year’s ASH Annual Meeting and Exposition spotlighted practice-changing research in malignant and benign hematology.

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December 17, 2021
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VIDEO: Combining dasatinib with prednisone, blinatumomab appears safe in ALL subtype

Combining the tyrosine kinase inhibitor dasatinib with prednisone and blinatumomab seemed safe in older patients with Philadelphia chromosome-positive acute lymphoblastic leukemia, researchers reported.

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December 17, 2021
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VIDEO: Inotuzumab ozogamicin shows ‘encouraging’ results in high-risk ALL population

Inotuzumab ozogamicin was well tolerated among patients with acute lymphoblastic leukemia who had undergone allogenic transplantation in a small study.

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