Concurrent ADT, radiation therapy improves outcomes in localized prostate cancer

ByAshley Killen

ByAmar U. Kishan, MD

Fact checked byMindy Valcarcel, MS

Androgen deprivation therapy sequencing had a considerable effect on outcomes among men with prostate cancer who received prostate-only radiotherapy, according to study results published in Journal of Clinical Oncology.

Historically, men with prostate cancer begin ADT before they start radiation.

However, the findings of this study — in which researchers analyzed more than 7,000 men treated across 12 randomized trials — suggest most men should begin ADT when starting radiation.

Healio spoke with Amar U. Kishan, MD, vice chair of clinical and translational research and chief of the genitourinary oncology service in the department of radiation oncology at UCLA Jonsson Comprehensive Cancer Center, about the results and their potential clinical implications.

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Sources/Disclosures

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Source:

Ma TM, et al. J Clin Oncol. 2022;doi:10.1200/JCO.22.00970.

Disclosures: Kishan reports research funding from, stock or other ownership in, and honoraria from ViewRay, as well as a consulting/advisory role with Janssen. Please see the study for all other authors’ relevant financial disclosures.

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Concurrent ADT, radiation therapy improves outcomes in localized prostate cancer

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