Localized Prostate Cancer
Early adverse effects from prostate cancer therapy predict long-term complications
Men who experience acute adverse effects after radiation therapy for prostate cancer may be at higher risk for more serious long-term urinary and bowel complications, according to results of a meta-analysis published in Lancet Oncology.
Many older men with prostate cancer and limited life expectancy are overtreated
More men with limited life expectancy and certain localized prostate cancers have received definitive treatment over the past 2 decades despite shifts toward active surveillance, according to results of a retrospective study.
Patient-centered care must account for uncertainty, anxiety during active surveillance
Although patients undergoing active surveillance for low-risk cancers generally have a favorable prognosis, oncologists should take steps to manage any anxiety and helplessness patients may be experiencing, according to a viewpoint paper.
AI model identifies tumor volume as risk factor for prostate cancer metastasis, recurrence
An AI model revealed tumor size to be an independent factor when determining risk for prostate cancer recurrence or metastasis, according to results of a retrospective study.
‘Compelling’ results: SBRT may be efficacious for low-, intermediate-risk prostate cancer
Five-fraction stereotactic body radiotherapy proved noninferior to conventional radiotherapy with regard to biochemical or clinical failure for men with localized prostate cancer, according to randomized phase 3 study results.
Proton therapy, IMRT comparably effective for low-, intermediate-risk prostate cancer
Photon and proton beam radiation therapies conferred similar outcomes for men with localized prostate cancer, according to results of a randomized phase 3 trial.
Long-term data support active surveillance as effective strategy for prostate cancer
Active surveillance for men with favorable-risk prostate cancer is an effective management strategy, according to data from a prospective cohort study published in JAMA.
Delaying therapy for localized prostate cancer does not affect long-term survival
Men with localized prostate cancer exhibited low risk for disease-specific mortality regardless of their assigned treatment, according to study results published in The New England Journal of Medicine.
Concurrent ADT, radiation therapy improves outcomes in localized prostate cancer
Androgen deprivation therapy sequencing had a considerable effect on outcomes among men with prostate cancer who received prostate-only radiotherapy, according to study results published in Journal of Clinical Oncology.
Addition of hormone therapy to radiotherapy benefits men with localized prostate cancer
The addition of androgen deprivation therapy to radiotherapy improved survival outcomes among patients with localized prostate cancer, according to study results published in The Lancet Oncology.