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Neuroendocrinology News
VIDEO: Pituitary and adrenal research highlights from ECE 23
In this video exclusive, Maria Fleseriu, MD, FACE, reviews the pituitary and adrenal research highlights presented at ECE 2023, the annual meeting of the European Society of Endocrinology, which took place in Istanbul, Turkey, in May.
Addressing glucocorticoid withdrawal syndrome in treatment of Cushing’s syndrome
To achieve optimal outcomes in Cushing’s syndrome, both clinicians and patients need to be prepared for the type and duration of symptoms that patients may experience during treatment and recovery.
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Most pituitary microadenomas do not change in size over 5 years of follow-up
Most adults with incident pituitary microadenomas have no change in size or a decrease in size during a median follow-up of nearly 5 years, according to findings published in Annals of Internal Medicine.
FDA approves spinal cord stimulation system for diabetic pain
The FDA has approved the Proclaim XR spinal cord stimulation system to treat painful diabetic peripheral neuropathy, manufacturer Abbott announced in a press release.
Cushing’s syndrome treatment maintains reductions in urinary free cortisol for 12 months
Most adults with Cushing’s syndrome receiving levoketoconazole twice daily maintained reductions in mean urinary free cortisol levels during a 12-month maintenance period, according to findings from the SONICS study extended evaluation.
Presence of type 2 diabetes in acromegaly increases mortality and morbidity risks
Among adults with acromegaly, concomitant type 2 diabetes was associated with increased risks for overall mortality and for cardiovascular mortality and morbidity, researchers reported in The Journal of Clinical Endocrinology & Metabolism.
Osilodrostat normalizes urinary free cortisol in Cushing’s disease for most at 72 weeks
More than 80% of adults with Cushing’s disease receiving osilodrostat had normalized mean urinary free cortisol levels at 72 weeks of treatment, according to findings from the LINC 3 study extension.
Endoscopic surgery confers higher acromegaly remission rate than microscopic surgery
Endoscopic transsphenoidal surgery has the best remission rates and fewest postoperative complications for adults with acromegaly, according to findings from a systematic review.
More than 15% of patients at risk for rare cancers missed screenings during COVID
CHICAGO — In rare hereditary cancers such as paraganglioma/pheochromocytoma, where patients travel for their care, COVID caused a disruption in their screening and treatments, according to a poster presented during ASCO Annual Meeting.
Sleep deprivation may prevent counterregulatory adaptation to recurrent hypoglycemia
In a cohort of healthy young adult men, one night of sleep deprivation attenuated the adaptation to recurrent hypoglycemia by preserving neuroendocrine counterregulation and subjective awareness, according to study findings.
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