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Bone/Mineral Metabolism News

Three osteoporosis risk assessment tools underperform in younger postmenopausal women
Three risk assessment tools struggled to detect osteoporosis based on bone mineral density T-scores among women aged 50 to 64 years, researchers reported in a study published in JAMA Network Open.
Cocoa extract, multivitamin supplements do not lower fracture risk for older adults

Multivitamin and cocoa extract supplements do not protect against clinical fractures for older adults, according to data published in the Journal of Bone and Mineral Research.
Two new denosumab biosimilars earn FDA approval

The FDA has approved two new biosimilars of denosumab for all indications of the reference medications Prolia and Xgeva, according to a press release from Celltrion.
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Baseline BMD T-score can help determine first-line therapy for women with osteoporosis

Women with osteoporosis have at least a 50% chance of reaching their target bone mineral density at 3 years if they have a BMD T-score of at least –2.8 at the total hip or –3.1 at the lumbar spine at baseline, according to study findings.
VIDEO: Hormone therapy protects bone, heart, brain health during menopause
In this Healio Video Exclusive, Caroline T. Nguyen, MD, speaks with Donna Shoupe, MD, about the health benefits of menopausal hormone therapy for women.
Abdominal aortic calcification detected during bone imaging tied to CV risk

Machine learning may be able to identify older adults most at risk for major adverse cardiovascular events by assessing abdominal aortic calcification in vertebral fracture assessment images, according to study data.
FDA approves two new biosimilars of denosumab

The FDA has approved two new biosimilars of denosumab to treat osteoporosis, increase bone mass, prevent skeletal-related events for people with multiple myeloma and other indications, Samsung Bioepis announced.
‘Alternative’ markers of insulin resistance can predict osteoarthritis

Surrogate measures of insulin resistance, based on the triglyceride-glucose index, can be used to predict the development of osteoarthritis, according to data published in Scientific Reports.
About 31% of weight lost by adults during GLP-1 therapy comes from lean mass

Lean mass constituted 30.8% of total body weight lost for adults who received a GLP-1 drug during a randomized controlled trial, according to findings published in Obesity.
Endocrinology Drug and Device Update
In a review of the 2024 milestones, Healio | Endocrine Today compiled a list of drugs and devices related to the field that were newly approved, cleared or had label or indication changes. Information was gathered from the FDA website and news releases. We put our best effort into making a complete list and regret any omission. Appearance of a drug or device does not constitute any endorsement by Healio | Endocrine Today, its editors, publishers or editorial board. — The Editors
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Headline News
Societies take stand against off-brand GLP-1s over safety concerns
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Headline News
THA stem design may have a larger impact on periprosthetic fracture risk vs. cement use
February 06, 20251 min read -
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Self-perceived stress linked to cryptogenic ischemic stroke in young women
March 14, 20253 min read
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Headline News
Societies take stand against off-brand GLP-1s over safety concerns
March 17, 202515 min read -
Headline News
THA stem design may have a larger impact on periprosthetic fracture risk vs. cement use
February 06, 20251 min read -
Headline News
Self-perceived stress linked to cryptogenic ischemic stroke in young women
March 14, 20253 min read