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Bone/Mineral Metabolism News
Identifying, treating patients with COPD plus diabetes, COPD plus osteoporosis
PHILADELPHIA — In addition to COPD, patients frequently have other chronic diseases on top of their lung disease, including type 2 diabetes and osteoporosis, according to a presentation at the 2024 GOLD COPD International Conference.
Lower SHBG concentrations tied to reduced fracture risk for men
Men with lower concentrations of sex hormone-binding globulin may be less likely to sustain a fracture than those with higher levels, according to data published in The Journal of Clinical Endocrinology & Metabolism.
Older women with CKD on denosumab may have a higher risk for hypocalcemia
Older women with chronic kidney disease who take denosumab may have a higher risk for emergently treated hypocalcemia compared with those treated with bisphosphonates, according to published data.
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Reducing sedentary behavior may lower clinical fracture risk for older men
The risk for clinical fractures is higher for older men who spend a higher proportion of their day performing sedentary behavior rather than physical activity or sleeping, according to new findings.
Parathyroid hormone therapy normalizes calcium for most with hypoparathyroidism
The majority of adults with hypoparathyroidism achieved normal serum calcium levels with palopegteriparatide at 1 year without supplemental vitamin D or calcium, according to data from a phase 3 open-label extension.
Loss of lean soft tissue may correlate with BMD changes for some adults with CKD
Changes in body composition may correlate with bone mineral density fluctuations in non-dialysis-dependent chronic kidney disease, according to a cohort study.
Oral achondroplasia therapy receives FDA breakthrough therapy designation
An oral medication to treat children with achondroplasia has received breakthrough therapy designation from the FDA, BridgeBio Pharma announced.
Fracture risk among Asian, Hispanic postmenopausal women may differ by origin subgroup
The risk for fractures among postmenopausal women may vary between ethnic origin groups, according to findings from the Women’s Health Initiative published in The Journal of Bone and Mineral Research.
Palopegteriparatide earns FDA approval for treatment of hypoparathyroidism
A parathyroid hormone prodrug developed to treat hypoparathyroidism received FDA approval, according to an industry press release.
Poor physical function may lead to higher fracture risk for women with type 2 diabetes
Worse physical function may be the factor contributing to an increased fracture risk for women aged 75 to 80 years with type 2 diabetes, according to a study published in JAMA Network Open.
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Headline News
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