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Neuroendocrinology News
Oral nonsteroidal treatment reduces glucocorticoid dose in congenital adrenal hyperplasia
Adults with congenital adrenal hyperplasia receiving an oral corticotropin-releasing factor type 1 receptor antagonist had a greater reduction in daily glucocorticoid dose at 24 weeks than placebo, according to top-line phase 3 trial data.
Oral acromegaly agent reduces IGF-1 levels below upper limit of normal for most adults
More than 80% of adults with acromegaly achieved an insulin-like growth factor level at or below the upper limit of normal at 36 weeks with an investigational once-daily oral medication, according to topline results from a phase 3 trial.
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Adults with Cushing’s syndrome report high burden of illness, despite ongoing treatment
Adults with endogenous Cushing’s syndrome reported that the condition moderately affects their quality of life and causes them to have symptoms about 16 days in a given month, according to findings published in Pituitary.
Cardiometabolic comorbidities more likely for adults with acromegaly than without
Cardiometabolic comorbidities, such as hypertension, cardiac arrythmias and diabetes, are more common in adults with acromegaly than those without the condition, according to a systematic review and meta-analysis published in Pituitary.
FDA approves once-weekly human growth hormone for children with GH deficiency
The FDA in June approved a once-weekly human growth hormone analog for children aged 3 years and older with growth hormone deficiency, according to a company press release.
Most adults with acromegaly achieve normal IGF-I levels with long-acting pasireotide
More than half of adults with acromegaly receiving the somatostatin receptor ligand pasireotide achieved normal insulin-like growth factor I levels, according to data from a long-term real-world study.
Genetic aspects of pituitary tumors: A conversation with Márta Korbonits, MD, PhD, DSc
Márta Korbonits, MD, PhD, DSc, FRCP, uncovered a passion for endocrinology from a series of inspirational lectures during her medical training.
VIDEO: Pituitary research presented at ENDO 2023
CHICAGO —In this video exclusive, John Carmichael, MD, discusses some of the pituitary research presented at ENDO 2023, including treatments for Cushing’s syndrome and adipose effects following acromegaly cure.
VIDEO: Chronic hormonal effects to look for following traumatic brain injury
CHICAGO—In this video exclusive, Tamara Wexler, MD, PhD, discusses evaluation and treatment of pituitary hormone deficiencies that can occur after acquired brain injury, from mild to severe concussions.
A coming ‘renaissance in endocrinology’: A conversation with R. Scott Struthers, PhD
R. Scott Struthers, PhD, had a lab job synthesizing peptide hormones as a college freshman. That experience launched a career featuring discovery of novel agents for endocrine diseases, women’s health conditions and cancers.
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Headline News
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November 14, 20245 min read -
Headline News
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Headline News
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