Bone/Mineral Metabolism News

Adults with nonalcoholic fatty liver disease and type 2 diabetes had impaired collagen type 1 C-telopeptide suppression in response to an oral glucose tolerance test but not after an IV glucose infusion, study data show.

Patients who used long-term inhaled corticosteroids to treat their COPD were at moderately higher risk for upper extremity and hip fractures, according to findings published in Chest.

Older adults with well-controlled type 2 diabetes assigned 4,000 IU daily vitamin D for 48 weeks saw no changes in insulin secretion rate or HbA1c vs. adults receiving placebo, study data show.

According to WHO, chronic noncommunicable diseases pose a significant threat to global public health and currently account for 70% of deaths worldwide. In the 1990s, as part of an increased focus on the burden of noncommunicable diseases, WHO identified osteoporosis as a future major health problem. To address this problem, researchers sought to create a tool designed to predict those at future risk for fragility fracture.

Feb. 26 through March 4 is National Eating Disorders Week, a time to put a greater spotlight on conditions such as bulimia nervosa, binge-eating disorder and anorexia nervosa, according to the National Eating Disorders Association.

Children with congenital adrenal hyperplasia tend to have lower bone mineral density compared with healthy children, but body composition is similar, according to findings published in Clinical Endocrinology.

In women aged at least 80 years with osteoporosis, bone mineral density at the total hip, femoral neck and lumbar spine increased during 18 months with abaloparatide therapy compared with placebo, according to findings from the ACTIVE trial.

Abdominal aortic calcification scores assessed using densitometric lateral spine images at the time of bone mineral density testing may identify older women at higher risk for atherosclerotic vascular disease-related events or death, according to findings published in the Journal of Bone and Mineral Research.

Adults with thyroid cancer taking less than 115 µg per day or at least 145 µg per day of levothyroxine after thyroidectomy or radioiodine ablation therapy had an increased risk for fractures compared with those taking 115 to 144 µg per day, according to study findings.

In a small subset of postmenopausal women with osteoporosis and diabetes who were not prescribed antidiabetes medications, the osteoporosis drug denosumab was shown to modestly improve fasting serum glucose over 3 years compared with placebo, according to a post hoc analysis of the FREEDOM trial.