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Bone/Mineral Metabolism News
Hip fracture increases mortality risk for up to 10 years

In the year after experiencing a hip fracture, risk for death increases by 33% in men and 20% in women, with this risk continuing to persist for 10 years, according to a hospital-based registry analysis published in The Journal of Clinical Endocrinology & Metabolism.
Amgen, UCB resubmit biologic license application for romosozumab
Amgen and UCB have resubmitted a biologics license application to the FDA for romosozumab for the treatment of osteoporosis in postmenopausal women at high risk for fracture, according to a press release from both companies.
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First-time osteoporosis fractures offer 'window' to reduce repeat fractures

AMSTERDAM — Patients with osteoporosis who experience a fracture are at an immediate increased risk for sustaining another within 2 to 3 years, presenting a “unique window of opportunity” for treatment, according to a presentation at the EULAR Annual Congress. “
Low-dose glucocorticoid exposure increases osteoporotic fracture risk

Akhila Balasubramanian
Statin use may lower fracture risk after stroke
Adults prescribed statin therapy after a stroke were less likely to sustain a fracture vs. similar patients not prescribed statin therapy, according to findings from a population-based study conducted in Taiwan.
Osteoporosis cases could soar 300% among men

June is Men’s Health Month, an annual commemoration intended “to heighten the awareness of preventable health problems and encourage early detection and treatment of disease among men and boys,” according to MensHealthMonth.org.
USPSTF backs osteoporosis screening in women, not men
In an update to its 2011 recommendations, the U.S. Preventive Services Task Force recommends screening with bone measurement testing to prevent osteoporotic fractures in women aged at least 65 years and in postmenopausal, high-risk women younger than 65 years.
Weight loss influences bone parameters in older adults

Older adults experiencing long-term or recent weight loss of at least 5% showed deterioration in both cortical and trabecular bone density and microarchitecture, especially at the weight-bearing skeleton, according to findings published in the Journal of Bone and Mineral Research.
Zoledronic acid may slow cancer treatment-induced bone loss in premenopausal women

Premenopausal women with hormone receptor-positive early-stage breast cancer randomly assigned zoledronic acid during chemotherapy experienced an increase in bone mineral density over 2 years vs. women assigned placebo, according to findings published in Bone.
In women, type 1 diabetes associated with rheumatic disease, autoimmune conditions
Women with type 1 diabetes are nearly three times more likely to develop systemic rheumatic disease vs. men with diabetes, increasing their likelihood of developing other nonrheumatic autoimmune conditions, according to findings published in the Journal of Diabetes and Its Complications.
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