Bone/Mineral Metabolism News

In adults with slightly elevated parathyroid hormone following Roux-en-Y gastric bypass surgery, supplementation with either calcium carbonate or calcium citrate did not restore normal PTH level, according to findings published in Clinical Endocrinology.

A lower mean vitamin D-binding protein level may be associated with a larger increase in free vitamin D for healthy white men after vitamin D supplementation, with the opposite effect observed in healthy Asian men, according to findings published in Clinical Endocrinology.

Adults born preterm with very low birth weights may face increased risk for metabolic syndrome, according to findings published in The Journal of Clinical Endocrinology & Metabolism. metabolic syndrome,” Chandima Balasuriya, MD, of the department of clinical and molecular medicine at Norwegian University of Science and Technology, and colleagues wrote in the study background. “Globally, around 15 million preterm births occur annually. ... A substantial number is also born small for gestational age at term. Most studies have addressed metabolic profile in individuals with low birth weight born premature or without specified gestational age. Adults born very preterm or at very low birth weight have been reported to exhibit higher blood pressure than term-born adults with normal weight.” a follow-up study, Balasuriya and colleagues analyzed data from two cohorts of white adults born between 1986 and 1988, including 55 adults born preterm with very low birth weights (< 37 weeks and weighing 1,500 g), 59 adults born at full term but small for gestational age ( 37 weeks; birth weight in the 10th percentile or lower) and 75 adult healthy controls.

The glycoprotein sclerostin, a negative regulator of bone formation, is associated with a measure of insulin resistance in children and adolescents, with the association much stronger in youths with obesity, according to study findings published in Bone.

Adults with obesity who undergo Roux-en-Y gastric bypass surgery are more likely to sustain a fracture independent of the amount of weight loss or diabetes status, with the risk for fracture rising over time, according to a study published in the Journal of Bone & Mineral Research.

Incident fractures may be predicted by physical performance and appendicular lean mass, independent of previous falls and FRAX probability, according to findings published in the Journal of Bone and Mineral Research.

The National Osteoporosis Foundation and Medtronic are launching a joint partnership to educate clinicians and the public about vertebral compression fractures and available treatment options to increase positive health outcomes related to osteoporosis management, according to a press release.

In vitamin D sufficient children and teens, 25-hydroxyvitamin D supplementation over 12 weeks did not influence changes in muscle mass, strength or composition, contradicting findings from similar studies conducted in adults, according to research published in the Journal of Bone and Mineral Research.

Most older breast cancer survivors prescribed anti-estrogen therapy do not undergo the recommended bone density screening to monitor the effects of treatments on osteoporosis risk, according to a database analysis published in Bone.

The rate of osteoporosis medication initiation for older adults hospitalized for hip fracture has fallen steadily during the past decade, according to an insurance claims database analysis published in JAMA Network Open.