Bone/Mineral Metabolism News

High body fat percentage coupled with low BMI increases the risk for sarcopenia in older adults with diabetes, according to findings from researchers in Japan.

Among postmenopausal women, two key bone turnover markers do not independently predict hip fracture risk after controlling for several factors, including fall history, BMI, and vitamin D and calcium intake, according to findings presented at the North American Menopause Society annual meeting.

Compared with women, men are at greater risk for a subsequent fracture, particularly within the first year and up to the first 3 years, after an initial major osteoporotic fracture, but refracture risk declines over time for both sexes, according to data presented at the American Society for Bone and Mineral Research Annual Meeting.

Older adults assigned to a high dose of daily vitamin D supplementation were more likely to develop hypercalciuria over 3 years vs. those assigned to a lower daily dose of the supplement, with the condition resolving after reducing calcium intake, according to findings from the Calgary Vitamin D study presented at the American Society for Bone and Mineral Research Annual Meeting.

Researchers found higher advanced glycation end-product content — associated with decreased bone strength — in the cortical bone of men with vs. without type 2 diabetes, according to data presented at the American Society for Bone and Mineral Research Annual Meeting.

Bone mineral density at the femoral neck and total hip is a potential surrogate for fracture risk in clinical trials of osteoporosis drugs, according to findings presented at the American Society for Bone and Mineral Research Annual Meeting.

Dual-task functional power and mobility training was shown to improve muscle power, reaction time and mobility and limit multiple falls for older adults in a study presented at the 2018 ASBMR annual meeting.

Discontinuing the use of bisphosphonates for more than 2 years has been linked to increase risk for hip fracture in women, according to research presented at the ASBMR 2018 annual meeting.

When combined with measurements of bone mineral density at the femoral neck, sarcopenia is not an effective predictor of major osteoporotic fracture risk, according to findings presented at the ASBMR 2018 annual meeting.

Despite a drop in fracture rates among U.S. adults aged at least 50 years between 2007 and 2013, fracture rates generally increased between 2013 and 2017, possibly because of a decline in DXA screening, according to findings presented at the ASBMR 2018 annual meeting.