Bone/Mineral Metabolism News

Her own early osteoporosis led endocrinologist Felicia Cosman, MD, to her groundbreaking work with anabolic medications and other important breakthroughs in osteoporosis treatments.

Japanese adults with type 2 diabetes were more than twice as likely to die of any cause in the 5 years after experiencing a hip fracture when compared with similar adults who did not sustain a hip fracture, according to findings published in the Journal of Diabetes Investigation.

Adults with rheumatoid arthritis and higher measures indicating frailty were more likely to sustain an osteoporotic fracture during 4 years of follow-up vs. similar patients with lower indicators of frailty, according to an analysis of Canadian registry data published in Bone.

In an analysis of real-world data, the use of SGLT2 inhibitors, GLP-1 receptor agonists and DPP-IV inhibitors were not associated with an increased risk for fracture in adults with type 2 diabetes, according to findings published in Osteoporosis International.

Women aged 80 and older with osteoporosis and substantial comorbidity have a high 5-year probability of hip fracture and may still benefit from drug therapy for prevention of hip fracture, according to a study published in JAMA Internal Medicine.

Bisphosphonate use before denosumab discontinuation was associated with less bone mineral density loss among postmenopausal women, according to findings presented at the EULAR Annual Congress.

SAN FRANCISCO — Adults with prediabetes assigned to daily vitamin D supplementation for 2.5 years were just as likely to develop type 2 diabetes during follow-up as similar patients assigned to placebo, regardless of baseline vitamin D status, according to study data presented here and published in The New England Journal of Medicine.

Among Japanese adults with type 2 diabetes the likelihood of developing sarcopenia rises as HbA1c increases, and the connection is driven primarily by decreases in skeletal muscle mass, according to findings published in the Journal of Diabetes Investigation.

Perimenopausal women with higher baseline levels of serum bone turnover markers and a lower trabecular bone score are at increased risk for presenting with osteopenia or osteoporosis at 5-year follow-up, according to findings published in Clinical Endocrinology.

Adults with higher parathyroid hormone and lower vitamin D levels are more likely to experience an episode of atrial fibrillation compared with those with normal measures, according to findings published in Nutrition, Metabolism and Cardiovascular Diseases.