Bone/Mineral Metabolism News

A cohort of female Olympic swimmers had lower bone mineral density measurements at all sites when compared with nonaquatic elite athletes, suggesting that weight-bearing or strength activities out of water could be incorporated into training to improve bone health, according to findings published in Bone.

A cohort of postmenopausal women with osteoporosis assigned the human monoclonal antibody romosozumab showed marked increases in dynamic parameters of bone formation just 2 months after initiating treatment when compared with women assigned placebo, according to findings published in the Journal of Bone and Mineral Research.

Men with type 2 diabetes and suboptimal free testosterone levels experienced an increase in osteoblastic activity with a concomitant increase in bone turnover when assigned to 22 weeks of biweekly intramuscular testosterone injections when compared with similar men who received placebo, according to findings published in the Journal of the Endocrine Society.

Among older adults, pain at multiple sites was associated with incident fracture risk in a dose-response manner, suggesting that widespread pain is an independent contributor to fracture risk, according to findings published in the Journal of Bone and Mineral Research.

Low bone mass often observed in adults with cerebral palsy is likely a reflection of poor bone accrual in early childhood rather than rapid bone loss, implying that clinicians should take steps to optimize patient bone health at an early age, according to findings published in Clinical Endocrinology.

The European Medicines Agency rejected the marketing authorization of the osteoporosis drug romosozumab, according to a press release from Amgen and UCB, citing potential cardiovascular risks as a major determining factor.

A cohort of women with osteoporosis who underwent routine bone mineral density monitoring in the 5 years after initiating therapy were less likely to experience a major osteoporotic fracture and more likely to adhere to treatment when compared with women who did not undergo monitoring, according to findings published in the Journal of Bone and Mineral Research.

It was summer of August 2014 when I sustained a compression vertebral fracture while vacationing with my family in Mackinac Island, Michigan. The diagnosis — a severe case of osteoporosis — was made 3 weeks later.

Survey data suggest that women with premature ovarian insufficiency or early menopause have “unmet information needs” regarding their increased risk for osteoporosis and often practice suboptimal bone health-related behaviors, such as low calcium intake and inadequate exercise, according to findings published in Clinical Endocrinology.

Women exposed to high levels of triclosan, an endocrine-disrupting chemical widely used as an antibacterial in consumer goods and personal care products, are more likely to have lower bone mineral density and evidence of osteoporosis at the intertrochanter when compared with women exposed to lower amounts of the chemical, according to findings published in The Journal of Clinical Endocrinology & Metabolism.