Bone/Mineral Metabolism News

Adults who take glucosamine supplements may be less likely to develop type 2 diabetes compared with those who do not take extra glucosamine, especially if they also have elevated levels of C-reactive protein, according to findings published in Diabetes Care. 

A cohort of children and adolescents with type 1 diabetes had markers of bone formation and bone resorption that were significantly decreased compared with children without diabetes, independent of diabetes duration and Tanner stages, according to findings published in Pediatric Diabetes.

Postmenopausal women with osteoporosis who received a single infusion of zoledronate after 2 to 5 years of denosumab therapy retained more than half of bone mineral density gained before stopping treatment with no increase in vertebral fractures, according to findings published in the Journal of Bone and Mineral Research.

Children born to mothers who smoked in early pregnancy were more likely to experience a fracture before age 1 year than those born to mothers who did not smoke, according to findings from a national register study published in BMJ.

Adults with abdominal obesity who participated in a mixed-meal tolerance test exhibited an acute postprandial suppression of bone turnover markers compared with the response after an oral glucose tolerance test, according to findings published in Bone.

Adults with pheochromocytoma or paraganglioma are nearly five times more likely to experience a vertebral fracture, a hallmark of osteoporosis, when compared with adults with nonfunctional adrenal tumors, according to findings published in Bone.

Women who experience a first fragility fracture are at significant risk for experiencing subsequent fractures, particularly in the 2 years after the fracture, according to findings published in the Journal of Bone and Mineral Research.

A cohort of children presenting with increased bone fragility and no extraskeletal signs of osteogenesis imperfecta tended to have a collection of common gene variants that predispose to osteoporotic fracture rather than a monogenic etiology of their condition, according to findings published in the Journal of Bone and Mineral Research.

A longer interval between denosumab injections is associated with suboptimal bone mineral density response at the spine and total hip, and strategies to improve the timely administration of denosumab in real-world settings are needed, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

Adults from India who live in areas with more air pollution have lower bone mineral content and bone mineral density compared with those living in areas with less fine particulate matter and black carbon in the air, according to findings published in JAMA Network Open.