Bone/Mineral Metabolism News

Higher glucocorticoid doses for adults with congenital adrenal hyperplasia may be associated with lower bone mineral density, especially among women and those prescribed prednisolone, according to findings published in Clinical Endocrinology.

A cohort of adults with type 2 diabetes assigned the GLP-1 receptor agonist liraglutide for 26 weeks experienced a preservation in hip and spine bone mineral density and no changes in bone resorption markers despite weight loss, suggesting the drug may have an antiresorptive effect, according to findings published in Bone.

Men with type 2 diabetes are more likely to develop osteoporosis if they have elevated follicle-stimulating hormone, or FSH, whereas elevated estradiol is associated with lower osteoporosis risk, according to findings published in the Journal of Diabetes.

In 2019, Healio readers were interested in fertility preservation for men on testosterone therapy, the wonders of metformin, possible associations between statins and diabetes, a new osteoporosis drug and more. 

Faster increases in bone turnover during the menopause transition and greater bone turnover during early postmenopause are risk factors for fracture, even among women with relatively preserved bone mineral density, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

In 2019, Healio readers were interested in the role of vitamin D and prescription fish oil supplements for cardiovascular health as well as studies exploring other uses of vitamin D. Also, not all dietary supplements are beneficial — or harmful — for people with diabetes.

Fractures may become less likely with supplement regimens that use calcium and vitamin D, but vitamin D supplements alone have not been shown to reduce risk, according to findings published in JAMA Network Open.

Bone mineral density at the lumbar spine and back pain history can be used in targeted case findings to identify children with the highest risk for prevalent vertebral fracture so that radiography can be used judiciously, according to findings published in the Journal of Bone and Mineral Research.

Several bioactive metabolites found in coffee may be associated with a beneficial effect on bone mineral density among healthy adults who report regular coffee consumption, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

Each month Endocrine Today reporters ask leading endocrinologists and diabetes educators about their resesarch and practices. Some of our recent Q&As are below.