Catching up on sleep during weekend may reduce hyperuricemia odds for postmenopausal women
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Key takeaways:
- Women who sleep less than 7 hours per night but catch up on sleep during weekend are less likely to develop hyperuricemia.
- Reduced odds for hyperuricemia were observed with 1 to 2 hours of extra weekend sleep.
Sleep-deprived postmenopausal women who catch up on their sleep over the weekend are less likely to have hyperuricemia than women who do not catch up on their sleep, according to findings published in Menopause.
“Many researchers have reported that weekend catch-up sleep is associated with a lower risk of hypertension, obesity and type 2 diabetes,” Eun-Ju Park, MD, of the department of family medicine at Pusan National University Yangsan Hospital in South Korea, and colleagues wrote. “The objectives of this research were to identify the association between weekend catch-up sleep and hyperuricemia in postmenopausal women with insufficient sleep duration and to determine whether weekend catch-up sleep can be another way to reduce hyperuricemia in Korean postmenopausal women.”
Researchers collected data from postmenopausal women who slept for an average of less than 7 hours per day. Data were obtained from the Korea National Health and Nutrition Examination Survey from 2016 to 2018. Demographics were collected through a survey. Average sleep duration was obtained from questionnaire responses. Weekend catch-up sleep was calculated by subtracting the average weekday sleep duration per day from the average weekend sleep duration per day. Serum uric acid was measured through blood samples. Hyperuricemia was defined as a serum uric acid level of 6 mg/dL or higher.
There were 1,877 women included in the study, of whom 614 caught up on sleep during weekends (mean age, 59 years) and 1,263 did not catch up on sleep (mean age, 65 years). More participants in the non-weekend sleep catch-up group had hyperuricemia than those who caught up on sleep (126 vs. 34; P < .001). After adjusting for confounders, women who caught up on sleep on weekends were 24.2% less likely to have hyperuricemia than those who did not catch up on sleep (adjusted OR = 0.758; 95% CI, 0.576-0.997).
Researchers examined associations between duration of weekend catch-up sleep and the odds for hyperuricemia. After adjusting for confounders, women who had 1 to 2 hours of weekend catch-up sleep were less likely to have hyperuricemia than those who did not catch up on sleep (aOR = 0.522; 95% CI, 0.323-0.845). However, there was no difference in hyperuricemia prevalence for women who had 0 to 1 hours of catch-up sleep or more than 2 hours of catch-up sleep than those who did not catch up with sleep on weekends.
“Maintaining good sleep duration benefits hyperuricemia, a risk factor for metabolic and cardiovascular diseases,” the researchers wrote. “If this is not possible, weekend catch-up sleep could be an alternative. Further studies, however, are required to identify the causal relationship between sleep recovery and hyperuricemia in postmenopausal women.”
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