May 06, 2016
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VIDEO: Moderate sedation shows promise for patients undergoing TAVR

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ORLANDO, Fla. — In this video, Jay S. Giri, MD, MPH, discusses a “minimalist” approach to transfemoral transcatheter aortic valve replacement.

At the Society for Cardiovascular Angiography and Interventions Scientific Sessions, Giri reported findings from an observational study of percutaneous transfemoral TAVR that demonstrated use of moderate sedation was associated with improved outcomes, including lower 30-day mortality and shorter length of hospital stay, compared with traditional general anesthesia.

“There has been a tremendous amount of interest over the last couple of years about ‘minimalist TAVR,’” Giri, assistant professor of cardiovascular medicine at the Perelman School of Medicine at University of Pennsylvania, said.

He noted that there are three general levels of moderate sedation: local anesthesia, conscious sedation and monitored anesthesia care with the presence of an anesthesiologist.

“The technique is getting more popular,” he said.

According to the results presented here, in about 12,000 patients in the STS/ACC TVT registry, rates of moderate sedation rose from early 2014 to June 2015.

“These are intriguing results which could end up having a great impact on the processes of care for TAVR in this era where over 90% of cases are being done transfemorally but still only 30%, roughly, are being treated with moderate sedation,” he said.