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Genetics/Genomics News
Premarket research not conducted for many CV devices subject to class I recall
Many recently recalled cardiovascular devices did not undergo premarket testing prior to FDA approval, and postmarket studies of the devices were slow and infrequent, researchers reported.
Platelet reactivity score may predict heart attack, stroke risk beyond BP, cholesterol
A platelet reactivity score that identifies people with a hyperreactive platelet phenotype can be used to determine those who might be at elevated risk for a cardiovascular event, researchers reported in Nature Communications.
Mental health ‘crucial’ after first-time hospitalization for heart disease
Risk for psychiatric disorder or suicide attempt is particularly high in the first year following hospitalization for heart disease, and patient support is important to lower such risk, researchers reported.
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Early age at menarche linked to carotid intima-media thickness
Genetically predicted early age at menarche was associated with increased carotid intima-media thickness, an early marker of subclinical atherosclerosis and medial hypertrophy, researchers reported.
U.S. News & World Report again ranks Cleveland Clinic No 1. for cardiology, heart surgery
For the 30th straight year, Cleveland Clinic topped U.S. News & World Report’s Best Hospitals rankings for cardiology and heart surgery.
Evinacumab safe, shows durable long-term LDL lowering in children with HoFH
Among pediatric patients with homozygous familial hypercholesterolemia and elevated LDL despite optimal lipid-lowering therapy, evinacumab durably reduced LDL and other significant lipid parameters out to 72 weeks, a speaker reported.
Ballantyne: Prevention of heart disease crucial, core of NLA’s mission
Prevention of heart disease will do more good in the long run than procedures to treat advanced heart disease, the incoming president of National Lipid Association said at the NLA’s Scientific Sessions.
Common ATTR amyloidosis gene could impair longevity among many Black carriers
A common cardiac amyloidosis-causing gene believed to be present in around 3% of the Black U.S. population is associated with increased risk for HF hospitalization and death, which increases with age, a speaker reported.
Phenotype-negative athletes with genetic heart disease OK to play sports
No athlete with a positive test for genetic heart disease but a negligible clinical phenotype had a genetic heart disease-associated death or cardiac event in more than 1,500 person-years of follow-up, researchers reported.
Genes may play role in heart attack risk during stressful times
ATLANTA — Adults genetically predisposed to high stress are more likely to have a heart attack during times of heightened stress, such as a major holiday or after a presidential election, researchers reported.
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