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Genetics/Genomics News
CRISPR gene-editing therapy shows promise as cardiac amyloidosis treatment in early study
CHICAGO — A CRISPR-Cas9-based therapy targeting the gene encoding transthyretin reduced transthyretin levels in patients with cardiac amyloidosis, researchers reported at the American Heart Association Scientific Sessions.
Clinician input essential in entire cardiology AI tool development process
Editor’s Note: This is part three of a three-part Healio Exclusive series on the development and use of AI to improve clinical outcomes in cardiovascular medicine and considerations for regulatory labeling and patient privacy .
AI in cardiology: A call for robust validation, regulatory labeling and security of data
Editor’s Note: This is part two of a three-part Healio Exclusive series on the development and use of AI to improve clinical outcomes in cardiovascular medicine and considerations for regulatory labeling and patient privacy.
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AI stands to change cardiology practice, but guidance, evidence of benefit are needed
Editor’s Note: This is part one of a three-part Healio Exclusive series on the development and use of AI to improve clinical outcomes in cardiovascular medicine and considerations for regulatory labeling and patient privacy .
VIDEO: ‘Clear lack of data’ on digital CV health tools for women concerning
In this Healio video exclusive, Sana M. Al-Khatib, MD, professor of medicine at Duke University School of Medicine, discusses barriers to developing cardiovascular digital health solutions for women.
AHA announces late-breaking lineup to be presented at 2024 Scientific Sessions
The American Heart Association Scientific Sessions will be held in-person only in Chicago from Nov. 16 to 18 and will feature eight late-breaking science sessions during the 3-day meeting.
Death from congenital heart disease disproportionately affects Black infants
Congenital heart disease-related deaths from 2005 to 2019 were more prevalent among Black vs. white infants, a gap that persisted year after year, a speaker reported at the American Academy of Pediatrics National Conference & Exhibition.
Plozasiran lowers triglycerides, reduces pancreatitis risk in chylomicronemia
In patients with persistent chylomicronemia, plozasiran, a small interfering RNA therapy, was associated with lower triglyceride levels and reduced risk for pancreatitis, researchers reported at the European Society of Cardiology Congress.
Premarket research not conducted for many CV devices subject to class I recall
Many recently recalled cardiovascular devices did not undergo premarket testing prior to FDA approval, and postmarket studies of the devices were slow and infrequent, researchers reported.
Platelet reactivity score may predict heart attack, stroke risk beyond BP, cholesterol
A platelet reactivity score that identifies people with a hyperreactive platelet phenotype can be used to determine those who might be at elevated risk for a cardiovascular event, researchers reported in Nature Communications.
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