Primary Immunodeficiency Disease News

Patients with diagnoses of various IgE deficiencies do not share equal odds for developing malignancies, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice.

ANAHEIM, Calif. — Updates in immunodeficiency and immune disorders were a highlight of this year’s American College of Allergy, Asthma & Immunology Annual Scientific Meeting, Douglas H. Jones, MD, FAAAAI, FACAAI, told Healio.

ANAHEIM, Calif. — Use of steroids and B-cell depleting therapies may lead to secondary immunodeficiencies, according to a presentation at the American College of Allergy, Asthma & Immunology Annual Scientific Meeting.

ANAHEIM, Calif. — A woman who could not tolerate immunoglobulin replacement therapy benefitted from C1-INH replacement therapy, according to a presentation at the American College of Allergy, Asthma & Immunology Annual Scientific Meeting.

Racial and ethnic disparities in mortality due to inborn errors of immunity indicate an urgent need to identify and remove barriers in care, according to a study published in The Journal of Allergy and Clinical Immunology.

PARK CITY, Utah — A bidirectional link exists between sleep quality and immune system performance, according to a presentation at the Association of PAs in Allergy, Asthma and Immunology Annual Allergy, Asthma & Immunology CME Conference.

Between 40 and 80 infants are born with severe combined immunodeficiency disorder each year in the United States and Canada. The disease is fatal without bone marrow transplants as infections overwhelm compromised immune systems.

Five-year survival rates among children with severe combined immunodeficiency remained stable at 72% to 73% from 1982 to 2009 before improving to 87% from 2010 to 2018, according to a study published in The Lancet.

Daily treatment with mavorixafor improved outcomes among patients with warts, hypogammaglobulinemia, infections and myelokathexis, or WHIM syndrome, in the 4WHIM phase 3 clinical trial, according to the drug’s developer, X4 Pharmaceuticals.

Healio compiled the most-read news in allergy, asthma and immunology posted in April.