Top news of October: Epinephrine nasal spray, cannabis and asthma, cat allergy, more
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Healio compiled the most-read news in allergy, asthma and immunology posted in October.
These reports included an epinephrine nasal spray, the impact of cannabis on people with asthma, cephalosporins for patients with penicillin allergies, treatment for cat allergy, sublingual immunotherapy for toddlers with peanut allergy, and more.
Epinephrine nasal spray outcomes comparable with injected delivery
Pharmacokinetic and pharmacodynamic responses to the neffy nasal epinephrine spray from ARS Pharma were comparable with responses to injected epinephrine, Thomas B. Casale, MD. Also, Brian Bizik, MS, PA-C, DFAAPA, and Jason Linde, MA, share their perspectives. Read more.
Cannabis use may increase mortality, morbidity from acute asthma exacerbations
Patients with asthma who used cannabis had increased risks for mortality, mechanical ventilation and altered mental status, according to a study of 406,800 patients presented at the CHEST Annual Meeting in Honolulu. Read more.
Q&A: Patients with verified penicillin allergies safely receive cephalosporins
As 50 patients received 77 unique cephalosporin courses or drug challenges, only one reacted to an aminocephalosporin, and none of the others had any reactions, said Ami P. Belmont, MD. Read more.
Cat allergy symptoms improve with holobetalactoglobulin lozenges
Patients with cat allergies experienced improvements in their symptoms with twice-daily use of a holo beta-lactoglobulin lozenge for 3 months, according to a pilot study published in Clinical and Translational Allergy. Read more.
Sublingual immunotherapy safely, effectively induces peanut allergy remission in toddlers
Not only did 78.9% of the per-protocol group of children age 1 to 4 years ingest the full 4,443 mg of peanut protein at month 36, Edwin H. Kim, MD, MS, but none of them required epinephrine either. Also, Scott H. Sicherer, MD, FAAP, and Jennifer A. Dantzer, MD, MHS, share their perspectives. Read more.
Oral, inhaled corticosteroids impose multiple burdens on quality of life in asthma
Burdensome events such as pneumonia, hoarse voice and oral thrush did not lead patients to halt asthma therapy, Vickram Tejwani, MD, but social stigma and psychosocial burdens may limit treatment adherence. Read more.
Tezepelumab reduces mucus plugs, improves lung function in adults with asthma
Reductions in mucus plug scores correlated with reductions in fractional exhaled nitric oxide levels and were associated with increased prebronchodilator FEV1, according to a study published in NEJM Evidence. Also, Praveen Akuthota, MD, ATSF, shares his perspective. Read more.
EAACI updates guidelines for diagnosing IgE-mediated food allergy
The update emphasizes the importance of clinical history, outlines when specific tests should be used and encourages regular reassessments, Alexandra F. Santos, MD, MSc, MRCPCH, FHEA, PhD. Also, Aikaterini (Katherine) Anagnostou, MD (Hons), MSc, PhD, shares her perspective. Read more.
FDA updates draft guidance on allergen cross-contact for food manufacturers
The guidance explains how to prevent cross-contact, ensure proper allergen labeling and prepare voluntary allergen advisory statements when appropriate. Also, Robert Earl, MPH, RDN, FAND, shares his perspective. Read more.