Most recent by Maurie Markman, MD
At least one symptom present in 72% of high-risk, early epithelial ovarian cancer cases
Despite benefits of catch-up series, HPV vaccination efforts must ‘remain on the young’
Emphasis on cancer prevention benefits can help overcome HPV vaccine hesitancy
HPV vaccination results in ‘real’ reduction in cervical cancer
Importance of HPV vaccination ‘impossible to overstate’
The role of initial maximal surgical cytoreduction in ovarian cancer still debated
There is considerable excitement in the gynecologic cancer research community with the pending results of several randomized phase-3 trials that examine the utility of antiangiogenic therapy in the management of ovarian cancer and with the early results of a number of targeted antineoplastic agents, including drugs that are known to inhibit poly (ADP-ribose) polymerase — or PARP.
HPV vaccination and the prevention of cervical cancer: a paradigm changing event
It is difficult to overstate the importance of data regarding the striking effectiveness of two different human papillomavirus vaccination strategies as a rational approach to prevent the development of cervical cancer. Available information about the vaccines reveals that, assuming a young woman has not previously been exposed to the specific HPV viruses included in either the bivalent or quadrivalent vaccine preparations and that she completes the planned vaccination schedule, the vaccination strategy is nearly 100% effective in preventing persistent infection. This is a recognized, essentially absolute, requirement for the subsequent development of this malignancy.