Sacroiliitis

CHICAGO — In patients with inflammatory bowel disease, a “strong and consistent three-way interaction” was identified between HLA-B27, male sex and the development of sacroiliitis, according to data presented at Digestive Disease Week.

Patients with axial spondyloarthritis demonstrate significant differences in peripheral and extra-musculoskeletal manifestations based on geographic region, according to data published in Rheumatology.

In patients with non-radiographic axial spondyloarthritis, MRI sacroiliitis and HLA-B27 positivity, but not elevated C-reactive protein or responses at week 12, predict long-term certolizumab pegol response, according to data.

A newly developed artificial neural network can accurately detect radiographic sacroiliitis in patients with suspected axial spondyloarthritis, according to data presented at ACR Convergence 2021.

Guselkumab administered once every 4 or 8 weeks improved axial outcomes in patients with psoriatic arthritis who have sacroiliitis through week 52, according to data published in The Lancet Rheumatology.

Artificial neural networks can assess and detect radiographic sacroiliitis, helping physicians to diagnose and classify axial spondyloarthritis, according to data presented at the American College of Rheumatology 2020 Annual Meeting.

As a general rule, rheumatologists are comfortable with ambiguous diagnoses, given that so many of the conditions they manage are marked by a wide spectrum of presentations and manifestations. A prime example is axial spondyloarthritis, which is divided into two categories: radiographic axial spondyloarthritis — also called ankylosing spondylitis — and nonradiographic axial spondyloarthritis. Discussion surrounding the nonradiographic form of this disease has been known to prompt the almost preposterous fundamental question: Is it even a thing?

HILTON HEAD, S.C. — In a duet session focused on spondyloarthritis, Grace Wright, MD, PhD, and Reeti Joshi, MD, detailed the differences between axial and peripheral disease and identified the various features of both in an effort to aid early diagnosis.