Osteoporosis

Published results showed application of calcium sulphate and hydroxyapatite biomaterial at the bone-implant interface may increase peri-implant bone formation in patients with osteoporosis and trochanteric fractures.

SAN FRANCISCO — A high prevalence of patients undergoing total hip arthroplasty were at high risk for osteoporosis but had a low prevalence of preoperative screening, according to results presented here.

Adults with osteoporosis who received a full course of denosumab were less likely to develop incident diabetes than those who discontinued denosumab after the initial dose, according to study data published in JAMA Network Open.

The FDA approved the first two denosumab biosimilars.

Calcium supplementation may be helpful for bone health and, possibly, reducing preeclampsia risk, according to an expert.

Long-term adherence to healthful or unhealthful plant-based diets was not associated with risk for hip fracture among postmenopausal women, according to cohort study results published in JAMA Network Open.

Exposure to heavy metals, such as arsenic, cadmium and mercury, was associated with lower anti-Müllerian hormone concentrations and/or increased decline during the menopause transition, researchers reported.

Exposure to higher levels of endocrine-disrupting chemicals may hinder bone development for children, adolescents and young adults, according to study findings published in Environmental Research.

The FDA has added a boxed warning for denosumab to advise patients with advanced chronic kidney disease of an increased risk for severe hypocalcemia, according to an FDA drug safety communication.

Machine learning algorithms can be effective in predicting osteoporosis among patients with rheumatoid arthritis, as well as identifying new predictive factors, according to data published in Nature Scientific Reports.