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March 08, 2024
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Low prevalence of osteoporosis screening found among high-risk patients undergoing THA

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Key takeaways:

  • About 53% of patients who underwent total hip arthroplasty met one criterion for osteoporosis screening.
  • However, only 12% of these patients underwent screening.

SAN FRANCISCO — A high prevalence of patients undergoing total hip arthroplasty were at high risk for osteoporosis but had a low prevalence of preoperative screening, according to results presented here.

“Hip arthroplasty surgeons should consider osteoporosis screening in these patients,” Amil R. Agarwal, BA, said in his presentation at the American Academy of Orthopaedic Surgeons Annual Meeting. “Follow-up studies could look at the actual efficacy of surgeon-initiated screening.”

OT0224Agarwal_AAOS_Graphic_01
Data were derived from Agarwal AR, et al. Paper 192. Presented at: American Academy of Orthopaedic Surgeons Annual Meeting; Feb. 12-16, 2024; San Francisco.

Using the PearlDiver database, Agarwal and colleagues stratified patients undergoing THA between 2010 and 2021 into groups based on whether they were at high risk or low risk for osteoporosis.

Amil R. Agarwal
Amil R. Agarwal

“To compare the high-risk vs. low-risk patients, we utilized Kaplan-Meier analysis that compared the 5-year cumulative incidence rates,” Agarwal said. “To control for confounders, we utilized Cox proportional hazard ratio model to look at the hazard ratios, 95% confidence intervals and P values.”

Agarwal said approximately 53% of patients who underwent THA met one criterion for osteoporosis screening. These patients were considered as being at high risk for osteoporosis. However, only 12% of these patients underwent screening for osteoporosis.

Patients at high risk for osteoporosis had a 1.6-fold higher risk for periprosthetic fractures (PPF) and a twofold higher risk for fragility fractures compared with patients at low risk for osteoporosis, according to Agarwal.

“The high risk vs. low risk increased risk of PPF or fragility fracture is important, but it shows that addressing screening and, ultimately, treatment could help reduce these morbid complications of PPF and fragility fracture in this population,” Agarwal said.