Insulin Resistance
Shift from NAFLD to MASLD does not necessarily require change in management
VANCOUVER, British Columbia — Despite recent changes in nomenclature for metabolic dysfunction-associated steatotic liver disease, an expert here noted that clinical pathways largely remain the same and require reinforcing.
Prioritize, optimize sleep to reap cardiometabolic benefits
BOSTON — Simple steps to optimize poor sleep habits can translate to large gains in cardiometabolic health, including improvements in BP, insulin resistance and even appetite regulation, according to a speaker.
Delaying mealtimes associated with greater insulin resistance
BOSTON — Delaying mealtime 5 hours after waking resulted in greater insulin resistance vs. delaying mealtime by a single hour, research presented at NUTRITION found.
Eating snacks of poor quality or at night reduces cardiometabolic health
BOSTON — Late-evening snacking was associated with unfavorable blood glucose and lipid levels, but consuming higher quality snacks may result in health benefits, according to researchers.
Adults with type 1 diabetes experience rise in glucose levels after COVID-19 booster
SAN DIEGO — Adults with type 1 diabetes may experience increases in glucose and insulin resistance in the days after receiving a COVID-19 booster vaccine, according to a presenter at the American Diabetes Association Scientific Sessions.
Early menopause linked to glucose metabolism changes, not other CV risk factors
Early menopause may be associated with increased insulin resistance, but researchers found no effects on other cardiovascular risk factors, according to a cross-sectional and longitudinal study published in Menopause.
Pegozafermin lowers high triglycerides, non-HDL and ApoB vs. placebo in small trial
Pegozafermin, a fibroblast growth factor 21 analog, reduced atherogenic particles in patients with severe hypertriglyceridemia and improved liver fat and insulin resistance compared with placebo, a speaker reported.
Low sex hormones may increase likelihood for transition to diabetes among Hispanic adults
Low testosterone among men and low sex hormone-binding globulin among women are associated with progression from prediabetes to diabetes, according to a study published in The Journal of Clinical Endocrinology & Metabolism.
Time-restricted eating does not alter insulin sensitivity, beta-cell function
An 8-hour time-restricted eating intervention did not improve insulin sensitivity, insulin secretion or beta-cell function in a small group of adults with overweight or obesity, according to data from a randomized controlled trial.
Weight loss of 10% significantly affects insulin resistance, cardiometabolic biomarkers
Among adults with overweight or obesity, weight loss of 10%, with or without physical activity, improved biomarkers of insulin resistance and cardiometabolic health, according to results of a secondary analysis of the Heart Health Study.