Insulin Resistance
Adults with type 1 diabetes experience rise in glucose levels after COVID-19 booster
SAN DIEGO — Adults with type 1 diabetes may experience increases in glucose and insulin resistance in the days after receiving a COVID-19 booster vaccine, according to a presenter at the American Diabetes Association Scientific Sessions.
Early menopause linked to glucose metabolism changes, not other CV risk factors
Early menopause may be associated with increased insulin resistance, but researchers found no effects on other cardiovascular risk factors, according to a cross-sectional and longitudinal study published in Menopause.
Pegozafermin lowers high triglycerides, non-HDL and ApoB vs. placebo in small trial
Pegozafermin, a fibroblast growth factor 21 analog, reduced atherogenic particles in patients with severe hypertriglyceridemia and improved liver fat and insulin resistance compared with placebo, a speaker reported.
Low sex hormones may increase likelihood for transition to diabetes among Hispanic adults
Low testosterone among men and low sex hormone-binding globulin among women are associated with progression from prediabetes to diabetes, according to a study published in The Journal of Clinical Endocrinology & Metabolism.
Time-restricted eating does not alter insulin sensitivity, beta-cell function
An 8-hour time-restricted eating intervention did not improve insulin sensitivity, insulin secretion or beta-cell function in a small group of adults with overweight or obesity, according to data from a randomized controlled trial.
Weight loss of 10% significantly affects insulin resistance, cardiometabolic biomarkers
Among adults with overweight or obesity, weight loss of 10%, with or without physical activity, improved biomarkers of insulin resistance and cardiometabolic health, according to results of a secondary analysis of the Heart Health Study.
Triglyceride glucose index may predict hypertension risk in rural Chinese adults
Elevated triglyceride glucose index and its dynamic change were positively associated with risk for incident hypertension among rural Chinese adults, according to research published in Nutrition, Metabolism & Cardiovascular Diseases.
Insulin resistance linked to poorer asthma outcomes
Patients with asthma and insulin resistance had lower and faster loss of lung function, as well as suboptimal responses to asthma treatments, according to a study published in American Journal of Respiratory and Critical Care Medicine.
Fatty pancreas increases diabetes risk, but may be reversible with weight loss
Adults with an elevated level of pancreatic fat have higher risk for developing incident diabetes, but weight loss may be able to lower diabetes risk by reducing fat levels and increasing pancreatic volume, according to a presenter.
Progressive beta cell dysfunction may be primary driver of impaired glucose tolerance
Loss of beta cell function serves as the basis for progression from normal glucose tolerance to impaired glucose tolerance, but insulin clearance may not be a major factor in the development of dysglycemia, according to a speaker.