Atherosclerotic Cardiovascular Disease

Among veterans with premature atherosclerotic CVD, women received less aggressive secondary prevention treatments compared with men and demonstrated lower levels of statin adherence in ischemic heart disease, researchers reported.

Significant therapeutic advancements have been achieved in the management of dyslipidemia. The ability to decrease LDL to previously unattainable levels, owing largely to the development of PCSK9 monoclonal antibodies, has illuminated two important lessons.

CV risk factors such as age, sex, smoking status, 10-year atherosclerotic CVD risk and certain biomarkers were independently associated with risk for future cancer, according to data published in JACC: CardioOncology.

Among veterans, recreational substance use was associated with a higher probability of premature and extremely premature atherosclerotic CVD, and the link was strongest in women, researchers reported in Heart.

Elevated non-HDL was associated with coronary artery calcification in mid-adulthood, with the strongest association among those with high non-HDL in adolescence, researchers reported in JAMA Cardiology.

The effects found with low-dose rivaroxaban plus aspirin are consistent regardless of patient BMI and weight, according to research published in the Journal of the American College of Cardiology.

Severe renal arteriosclerosis is associated with a nine times greater risk for atherosclerotic cardiovascular disease in patients with lupus nephritis, according to data published in Arthritis Care & Research.

Women who developed first-time gestational diabetes and returned to normal blood glucose levels after pregnancy may experience a twofold increased risk for developing atherosclerotic CVD, according to new data from the CARDIA study.

The first technique for coronary artery calcium scoring was published in 1990. Given the lack of data at the time on CAC and coronary atherosclerosis burden, the algorithm was remarkable yet unactionable.

Evolocumab, a PCSK9 inhibitor, in addition to statin therapy for stable atherosclerotic CVD may lower risk for future revascularization with PCI or CABG, according to findings published in the Journal of the American College of Cardiology.