Antibiotic

Two dozen biopharmaceutical companies recently announced the launch of the AMR Action Fund, a collaboration they hope will lead to the development of two to four new antibiotics by 2030.

Hospitalized patients who had a documented penicillin allergy had higher odds of receiving “inferior” antibiotics — some that could potentially cause adverse drug events, data published in JAMA Internal Medicine show.

Modification from oral to IV antibiotic administration led to increased complications and adverse effects after revision shoulder arthroplasty, according to published results.

Typhoid fever and paratyphoid fever are clinically indistinguishable and produce the syndrome known as enteric fever. Both are caused by Salmonella that infect only humans. Therefore, when the diagnosis of typhoid or paratyphoid fever is made, the origin is another human.

The most recent MMWR included a report about a novel, emerging strain of beta-lactamase-producing Neisseria meningitidis in the United States that is resistant to both penicillin and ciprofloxacin.

The prescribing of unnecessary antibiotics in U.S. physician offices and EDs decreased slightly, from 30% to 28%, between 2010 and 2015, according to findings published in Clinical Infectious Diseases.

Greater influenza vaccination uptake correlated with state-level reductions in antibiotic use, according to findings published in Open Forum Infectious Diseases.

Published results showed no statistically significant differences in the rate of surgical site infections after foot and ankle trauma surgery with use of 1g or 2g of cefazolin.

This episode delves into the history of Whipple’s disease — from its initial description, to the lengthy process of proving it’s an infectious disease.

Diagnoses of acute otitis media or suppurative middle ear infection relies chiefly on examination findings of the tympanic membrane. In 2013, the AAP revised its initial 2004 guidelines to include stringent diagnostic criteria and emphasized the need for accurate diagnosis of AOM and otitis media with effusion.