Antibiotic

A case-based reasoning, or CBR, algorithm offered appropriate antibiotic recommendations significantly narrower in spectrum than choices made currently in clinical practice, according to results from a study published in Clinical Infectious Diseases.

Day Zero Diagnostics Inc. has been awarded up to $6.2 million in funding from Combating Antibiotic Resistant Bacteria Biopharmaceutical Accelerator, or CARB-X, to accelerate the development of a new diagnostics system for combatting drug-resistant bacteria using machine learning and whole-genome sequencing.

A decrease in inpatient fluoroquinolone use, particularly in regard to ciprofloxacin, served as the primary driver behind a decrease in overall use of fluoroquinolones at Veterans Affairs, or VA, hospitals in a 3-year period, according to findings from a retrospective cohort study.

Accurate influenza diagnosis and vaccination could curtail unnecessary antibiotic use and help reduce the global threat of antibiotic resistance, according to findings in Clinical Infectious Diseases.

Accurate influenza diagnosis and vaccination could curtail unnecessary antibiotic use and help reduce the global threat of antibiotic resistance, according to findings in Clinical Infectious Diseases.

Patients in hospitals with an infectious disease specialist are treated with antibiotics in a manner more consistent with antibiotic stewardship principles, according to results published in Clinical Infectious Diseases.

Patients with nonvalvular atrial fibrillation and normal kidney function had increased bleeding risk with dabigatran when used alongside P-glycoprotein inhibitors diltiazem and verapamil, according to a retrospective comparative effectiveness cohort study published in JAMA Network Open.

Using Clinical and Laboratory Standards Institute, or CLSI, revised breakpoints and omitting extended-spectrum beta-lactamase, or ESBL, labeling in electronic medical records decreased the prescribing of carbapenem antibiotics and increased beta-lactam/beta-lactamase inhibitor use for infections due to ESBL producers, according to a single-center retrospective chart analysis.

All-cause readmission rates at 90 days among people who inject drugs and left the hospital against medical advice decreased when they were prescribed oral antibiotic therapy — including partial IV therapy and partial oral therapy — compared with patients who were not prescribed any antibiotics, according to findings in Clinical Infectious Diseases.

The number of antibiotic prescriptions a patient receives may increase that person’s likelihood of being admitted to the hospital, according to a study published in BMC Medicine.