Obsessive-Compulsive Disorder News

Children with pediatric acute-onset neuropsychiatric syndrome, or PANS, exhibited cerebral microstructural differences in multiple brain structures, according to results of a case-control study published in JAMA Network Open.

Researchers have gained new insight into the cognitive and computational process underlying obsessive-compulsive symptoms. Specifically, patients with obsessive-compulsive disorder may distrust their past experience, resulting in increased indecisiveness, uncertainty and exploratory behaviors, according to study findings published in PLoS Computational Biology.

Patients with obsessive-compulsive disorder generally do not benefit from mindfulness-based cognitive therapy, or MBCT, according to study results published in Psychiatry Research.

Deep brain stimulation of the ventral anterior limb of the internal capsule, or vALIC, in a regular clinical setting is effective and safe for treating treatment-refractory OCD, according to results of a clinical cohort study published in American Journal of Psychiatry.

Researchers have identified eight psychiatric disorders that share a common genetic structure, according to study results published in Cell.

Cognitive behavioral therapy may improve outcomes for anxiety-related disorders compared with control conditions up to 1 year after treatment completion, according to results of a systematic review and meta-analysis published in JAMA Psychiatry. Beyond 1 year, effects vary by specific disorder, researchers noted.

A nationwide population-based cohort study published in JAMA Psychiatry has reported the “first comprehensive assessment” of the incidence and risks of mental disorders in childhood and adolescence.

Results of a systematic review and meta-analysis suggest that cognitive behavioral therapy for pediatric obsessive-compulsive disorder symptoms shows promise, but its efficacy remains uncertain overall.

Children and adolescents with autism spectrum disorders who exhibit obsessive-compulsive disorder behaviors had significantly lower scores for OCD behaviors at 16 weeks when taking fluoxetine compared with placebo, according to findings published in JAMA. However, in prespecified analyses that accounted for several variables, the difference between the groups was nonsignificant.

Findings published in Psychiatry Research revealed significant overlap between self-reported PTSD and obsessive-compulsive disorder symptoms.