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Dermatology News
13-year-old boy with reddish-brown rash on leg
A 13-year-old boy presented to a pediatric dermatology clinic with a new reddish-brown rash on the left anterior leg. He first noticed the rash after getting a new iPad 3 months ago. He reported that he typically rests the iPad on his left thigh while he uses it, sometimes for several hours at a time. He denied pain or pruritus in the affected area. The rash had not been treated. He is an otherwise healthy teenager without complaints.
Children with early-onset vitiligo more likely to have extensive, progressive disease
Children who were diagnosed with vitiligo before 3 years of age were more likely to have progressive and extensive disease compared with those who developed later-onset childhood vitiligo, according to recently published study results.
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Standard adult dosing of Stelara efficacious in adolescents with psoriasis
VANCOUVER, British Columbia — Standard adult dosing of Stelara produced greater efficacy in adolescents with moderate-to-severe plaque psoriasis when compared with half dosing and placebo treatment in a 1-year study, according to research presented at the World Congress of Dermatology.
Dystrophic toenails in a 4-year-old boy
A 4-year-old boy presents with concern for toenail changes. His toenails were normal at birth. Nine months before presentation his mother noticed three of the nails on his left foot were yellow. These toenails have since darkened in color and have become thicker than his other nails. His fingernails are unaffected. He has no pain, and the remainder of his skin exam is normal. His parents have not attempted any treatment yet. The boy is bothered by the appearance of the nails and generally keeps his feet covered. His father has also noticed white debris on some of his toenails but denies thickening or discoloration.
Facial pruritus, erythema in an 11-year-old male
An 11-year-old male presents with the chief complaint of “poison ivy on his face.” The child had been hiking with his grandparents the day before, and had seen some poison ivy, but did not recall touching any. That evening, his face began to swell with some erythema. By the next morning, the rash had worsened, with intense pruritus, more swelling and erythema and some blisters. However, he did not complain of pain. He was taken to his primary provider’s office, where he received an injection of steroids, a prescription for oral and topical steroids and oral Benadryl.
Automated online counseling shows promise for adolescents with acne
Internet-based acne education that included automated counseling was not superior in improving acne severity or quality of life vs. standard website education, according to study findings.
FDA grants rare pediatric disease status to FCX-007 for recessive dystrophic epidermolysis bullosa
The FDA has granted rare pediatric disease designation to FCX-007 for the treatment of recessive dystrophic epidermolysis bullosa, according to the drug’s manufacturer.
Gene therapy effectively treats complications of Wiskott-Aldrich syndrome in children
In a small cohort of children and adolescents with Wiskott-Aldrich syndrome, autologous hematopoietic stem cell gene therapy led to clinical improvements in symptoms of autoimmunity, infectious complications and severe eczema, according to a press release.
Hyperpigmented, reticulated rash in a 15-year-old female
A 15-year-old female presents to your office with rash. She is afebrile and feels well. The patient reported that she noticed the rash 2 weeks before her appointment, and the color has gradually progressed from red to brown. She has not experienced a rash like this before. The patient does not take any medications other than ibuprofen, as needed, and is otherwise healthy. She plays basketball and rides horses.
European Commission approves Humira for treatment of chronic plaque psoriasis in children
AbbVie announced that Humira has received marketing authorization from the European Commission for the treatment of severe chronic plaque psoriasis in children and adolescents ages 4 years and older who do not respond to topical therapy or phototherapies.