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Dermatology News
More than a quarter of patients with acne reported nonadherence to treatment
Twenty-seven percent of patients with acne reported they did not fill all their prescriptions, with a higher percentage of nonadherence reported when multiple treatments were prescribed, according to data from a recently published study.
FDA advisory committee: Severe need for pediatric studies in AD
An FDA advisory committee agreed there is an unmet medical need for systemic products, drugs, and biologics, along with additional clinical studies, for the treatment of children with atopic dermatitis who do not respond adequately to topical therapy.
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Novel boron-based ointment safe in treating atopic dermatitis in children
AN2728 ointment 2%, a novel boron-based small-molecule ointment, might be effective for the treatment of patients ages 2 years and older with mild-to-moderate atopic dermatitis, according to research presented during a late-breaking research session.
Clindamycin, TMP-SMX comparably effective, safe for uncomplicated skin infections
Results from a multicenter, prospective, randomized double blind clinical trial indicate clindamycin and trimethoprim-sulfamethoxazole have comparable efficacy and safety for treatment of uncomplicated skin infections.
17-month-old febrile male with onset of rash, vomiting: Value of the ‘48-hour rule-out’
A 17-month-old boy was admitted to a children’s hospital for fever, vomiting and rash. For 2 days before admission, he had rhinorrhea but otherwise appeared healthy. The evening before admission, he developed a fever of 103.5°F and, later, started vomiting. Overnight, he developed a lacy rash on his legs and stomach that progressed to his arms.
Inguinal adenopathy with rash in a 6-year-old febrile female
A 6-year-old female is admitted from the ED for evaluation and treatment of a febrile illness with a rash. The history of her chief complaint began 8 days earlier when she noted a mildly painful lump in her right inguinal area. Less than 48 hours later, she noted the onset of a rash that first appeared in the same area as the right inguinal lump, but rapidly spread in every direction.
Breastfeeding duration may affect association between eczema risk, FLG variants
Longer duration of breastfeeding weakened the association between filaggrin gene variants and eczema development in early years of life, according to research presented at the American Academy of Allergy, Asthma and Immunology Annual Meeting in Houston.
Early treatment of infantile atopic dermatitis reduces food allergy incidence
Early, aggressive treatment of patients with infantile atopic dermatitis significantly reduced food allergy incidence by 18 months of age, according to research presented at the American Academy of Allergy, Asthma and Immunology Annual Meeting in Houston.
Topical pimecrolimus use in pediatric AD not associated with increased malignancy risk
Topical pimecolimus treatment in children with atopic dermatitis appeared to have no association with increased risk of malignancy when compared with other data, according to recently published study results.
Rash, swelling in a 2-year-old febrile girl
A 2-year-old girl presents to your office with fever and rash. She has had fever (Tmax 101.6°F) for 2 days. The rash began the day before presentation. It started as “red spots” on the legs, then spread. The patient has been itchy and fussy. Today she refused to walk, and her parents noticed her feet, as well as her hands, were swollen. Review of systems is notable for rhinorrhea. She does not take any medications and is otherwise healthy.