Biologics News

Kentucky researchers have described the perioperative complications and complication rates of transforaminal lumbar interbody spine fusion procedures with recombinant human bone morphogenetic protein-2.

Researchers have found an ultra-low-molecular weight heparin capable of reducing the incidence of venous thromboembolism in orthopedic surgery patients, according to the results of a large clinical program.

Using a novel approach of successively neutralizing the bactericidal factors of medical-grade honey, researchers have isolated an antibiotic protein called defensin-1 that accounts for honey’s well known antibacterial properties, according a study published in The Journal of the Federation of American Societies for Experimental Biology (FASEB).

Though much has been made of treatment involving platelet-rich plasma – from efficacy to formulations, hype, uses and potential – relatively little data exists to firmly support or refute its capabilities.

A new generation of cementless, ultraporous metal ingrowth materials may allow for more durable fixation of a knee implant to the bone in cases where biologic fixation has historically achieved less than optimal outcomes, according to an orthopedic investigator at the 2010 Current Concepts in Joint Replacement Spring Meeting, in Las Vegas.

Dr. Robert Heaney was a pioneer in osteoporosis research. He directed an entire metabolic wing in the medical school hospital where I trained some 50 years ago. I once mentioned that I did not understand osteoporosis. He said I would when I was 50 years of age — that either the medical community would learn more, I would learn more or both. I am well past 50 years, have 20 plus years of my own clinical research in osteoporosis and I still possess minimal understanding and have more questions than answers.

NEW ORLEANS – Prostaglandin EP-2 receptor agonist CP-533,536 demonstrated accelerated healing in patients with acute tibial fractures evaluated by an orthopedic panel but not a panel of radiologists, according to a study presented here.

Women who drank large amounts of tea had a significantly increased of risk of developing rheumatoid arthritis, whereas women who consumed coffee did not, according to a report from the Women's Health Initiative Observational Study.

An immune cell known to cause chronic inflammation in autoimmune disorders has been identified as a possible culprit in low back pain associated with herniated discs, according to investigators at Duke University Medical Center.

OSLO — Two-stage revisions that might involve an osteotomy or one-stage revisions preceded by an arthroscopy to examine the articular cartilage may be indicated when a high-level athlete’s reconstructed ACL fails, a British knee surgeon said at the 2010 ESSKA Congress, here.