Metacarpophalangeal OA is associated with mechanical factors
Click Here to Manage Email Alerts
Published results showed radiographic metacarpophalangeal osteoarthritis was associated with mechanical factors and was especially associated with severe radiographic proximal interphalangeal joint OA.
Using baseline data from the Digital Cohort Osteoarthritis Design, researchers evaluated the prevalence of radiographic metacarpophalangeal OA, defined as two or more metacarpophalangeal joints with a Kellgren and Lawrence score of 2 or greater, among 425 patients with symptomatic hand OA. Researchers compared the prevalence of metacarpophalangeal OA in the dominant and non-dominant hands, and studied the associations between radiographic metacarpophalangeal OA and patient characteristics using univariable and multivariable logistic regression.
Results showed 32.5% of patients had radiographic metacarpophalangeal OA; however, researchers noted no patients had severe metacarpophalangeal OA. Researchers found patients with metacarpophalangeal OA had a mean age of approximately 69.2 years, a BMI of approximately 25 kg/m2 and 86.2% were women. Researchers also noted metacarpophalangeal OA was more frequent in the dominant hand and predominated at the first and second metacarpophalangeal joints.
Older age, manual occupation, scaphotrapezial OA and a high number of proximal interphalangeal joints with radiographic OA were associated with metacarpophalangeal OA, according to results of the multivariable analysis. However, the analysis showed no association between metacarpophalangeal OA and metabolic syndrome or hand OA symptoms.
“The presence of [metacarpophalangeal] MCP OA without [proximal interphalangeal joint] PIP OA involvement should lead us to reconsider the diagnosis of [hand OA] HOA, which is consistent with the literature,” the authors wrote. “Further prospective studies are necessary to confirm longitudinally these cross-sectional results.”
Collapse
Read more about
Click Here to Manage Email Alerts