This article is more than 5 years old. Information may no longer be current.
Significantly higher infection risk seen with hemodialysis vs peritoneal dialysis after THA, TKA
Click Here to Manage Email Alerts
According to results, a significantly higher risk of infection was seen in patients on hemodialysis compared with patients on peritoneal dialysis after total hip or total knee arthroplasty.
Using Medicare files, researchers identified 531 patients who underwent TKA and 572 patients who underwent THA and were on peritoneal dialysis. Patients were matched 1:1 to patients on hemodialysis and 1:3 with patients who were not on either form of dialysis. Adverse events, which included prevalence of infection at 1 year and hospital readmission at 30 days, were determined with multivariate regression analysis.
Results showed the infection rate at 1 year after THA was 1.5% in patients on peritoneal dialysis and was 4.2% in those on hemodialysis, with an odds ratio of 0.3. At 1 year, the infection rate for patients who underwent TKA was 3.39% for those on peritoneal dialysis and was 6.03% for those on hemodialysis. Investigators noted patients on peritoneal dialysis had a similar infection rate compared with matched control patients. The rates of hospital readmission, emergency room visits, and mortality were similar in patients on peritoneal dialysis vs. hemodialysis; however, these rates were significantly higher than those of patients not on dialysis. – by Monica Jaramillo
Disclosures: Browne reports he is a paid consultant for Heron Therapeutics, Novartis and OsteoRemedies; is a board or committee member of American Association of Hip and Knee Surgeons, Southern Orthopaedic Association, Virginia Orthopaedic Association and the American Joint Replacement Registry; receives intellectual properties and is a paid consultant for DJ Orthopaedics; is on the editorial or governing board for, receives publishing royalties and receives financial or material support from the Journal of Arthroplasty; and receives publishing royalties and financial or material support from the Journal of Bone and Joint Surgery and Saunders/Mosby-Elsevier.
Click Here to Manage Email Alerts