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Preoperative opioid use correlated with increased revision, readmission rates after TKA, THA
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A correlation was seen between preoperative opioid use and significantly increased risks of early revision and 30-day readmission after patients underwent total knee arthroplasty or total hip arthroplasty, according to recently published results in the Journal of Bone and Joint Surgery.
Researchers reviewed data from two Truven Health MarketScan databases to identify patients who underwent TKA or THA. There were 324,154 patients identified with a 1-year follow-up and 159,822 patients identified with a 3-year follow-up. The National Drug Codes were used to identify preoperative opioid prescriptions. Investigators compared 30-day readmission rates and revision arthroplasty rates between groups of patients based on their duration of preoperative use in the 6 months prior to TKA or THA.
There were lower revision rates seen in opioid-naïve TKA patients compared with those with greater than 60 days of preoperative opioid use. Investigators noted the same trend among patients who underwent THA. The trends continued after age, sex and Charlson Comorbidity Index were adjusted.
According to researchers, the 30-day admission rate in patients who underwent TKA or THA was significantly lower in patients without preoperative opioid use vs. those with more than 60 days of preoperative opioid use. The correlation again continued after age, sex and Charlson Comorbidity Index were adjusted. – by Monica Jaramillo
Disclosures: Weick reports no relevant financial disclosures. Please see the full study for a list of all other authors’ relevant financial disclosures.
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