October 11, 2017
2 min read
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Within 1 year of spacer placement and removal of infected hip implant, 16% of patients retained spacers

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Results from this study demonstrated that at 1 year after removal of a total hip arthroplasty implant followed by placement of a cement spacer for periprosthetic joint infection, 16.8% of patients retained their spacers and 10.8% needed repeat debridement.

Perspective from Wael K. Barsoum, MD

Jourdan M. Cancienne

“[After] analyzing a national sample, only 60% of patients undergo reimplantation at 1 year following explantation and spacer placement for deep infection following total hip arthroplasty, suggesting that previous reports focusing on staged revision may overestimate the success of the procedure and neglect a not insignificant population of patients with retained spacers,” Jourdan M. Cancienne, MD, from the department of orthopedic surgery at the University of Virginia School of Medicine, told Healio.com/Orthopedics.

Using a national database, Cancienne and colleagues identified 7,146 Medicare patients who underwent removal of an infected hip prothesis and had placement of an antibiotic spacer. Multivariate logistic regression analysis was used to evaluate independent patient-related risk factors for in-hospital mortality, repeat debridement without reimplantation within 1 year, resection arthroplasty and reimplantation of a hip arthroplasty.

Results after 1-year postoperatively showed 464 patients died in a hospital setting, 775 patients had a repeat debridement, 404 patients had resection arthroplasty, 1,202 patients retained their spacers and 4,301 patients underwent reimplantation at an average of 124.4 days.

Risk factors for death included male gender, age older than 85 years, diabetes, congestive heart failure, chronic lung disease, liver disease and hemodialysis. Risk factors for repeat debridement, but not reimplantation, included obesity, inflammatory arthritis, depression, hyperlipidemia, chronic kidney disease and chronic liver disease. Female gender, age older than 85 years, diabetes, peripheral vascular disease, congestive heart failure, hemodialysis and depression were among the predictors for no reimplantation within 1 year. – by Monica Jaramillo

 

Disclosures: The researchers report no relevant financial disclosures.