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Gender cited as an independent risk factor for complications after primary TJA
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Recent study results have revealed sex as an independent risk factor for certain complications following total joint arthroplasty. Further, researchers observed differences between sexes regarding complications following total hip arthroplasty and total knee arthroplasty.
“We found that male gender was an independent risk factor for postoperative sepsis, myocardial infarction, and acute renal failure,” Darwin D. Chen, MD, assistant professor at the department of orthopedic surgery, adult reconstruction and hip preservation at The Mount Sinai Hospital in New York, told Healio.com/orthopedics. “Female gender was a risk factor for urinary tract infection, blood transfusion, and non-home discharge. While the overall complication rate is low, it is important to understand that males and females have different postoperative issues. This study can hopefully allow us to target these gender specific complications in an effort to reduce risk even further.”
Chen and colleagues used the national Surgical Quality Improvement Program database to identify patients who underwent total hip arthroplasty (THA) and total knee arthroplasty (TKA) between 2012 and 2014. The researchers divided patients according to their sex. They assessed correlations between sex, other patient characteristics and complications after THA or TKA with bivariate analysis and multivariate analysis. Additionally, they analyzed sex to determine whether it was an independent risk factor.
Regarding THA, 54.9% of the patients were women. Using multivariate analysis, the investigators found that female sex was a protective factor for mortality, sepsis, cardiovascular complications, unplanned reintubation and renal complications. However, female sex was an independent risk factor for urinary tract infection.
Women comprised 62.3% of the patients who underwent TKA. Multivariate analysis showed female sex as a protective factor for sepsis, cardiovascular complications and renal complications. Female sex, however, was an independent risk factor for urinary tract infection, blood transfusion and non-home discharge. – by Monica Jaramillo
Disclosure: Chen reports no relevant financial disclosures.
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