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Athletes with shoulder instability had significantly lower levels of specific collagen biomarker
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Athletes with shoulder instability had significantly lower levels of the cartilage degradation marker collagen type II cleavage compared to athletes without shoulder instability, according to results.
Brett D. Owens, MD, of the Warren Alpert Medical School of Brown University, and colleagues used commercially available enzyme-linked immunosorbent assay kits to compare preinjury collagen type II cleavage and procollagen II carboxy propeptide levels between 51 young athletes with shoulder instability and 210 athletes without documented ACL or shoulder instabilities.
Results showed patients who subsequently had shoulder instability had significantly lower mean preinjury collagen type II cleavage levels vs. the control group. However, researchers found no significant differences in preinjury procollagen II carboxy propeptide levels between the two groups.
“Genetic predisposition to shoulder instability is still being investigated,” Owens told Healio.com/Orthopedics. “This study suggests that preinjury cartilage metabolism profiles may be different in young athletes who experience shoulder instability.” – by Casey Tingle
Disclosures: Owens is a paid consultant for Mitek, Conmed, Linvatec and MTF. Please see the full study for a list of all other authors’ relevant financial disclosures.
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