August 02, 2016
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Study shows no weight change between TKA, non-TKA patients

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Patients with osteoarthritis who underwent total knee arthroplasty did not lose or gain more weight compared with patients who did not undergo total knee arthroplasty, according to the results of a prospective cohort study.

Researchers compared initial BMI, final BMI and change in weight over 72 months among 140 patients who underwent total knee arthroplasty (TKA) during the Osteoarthritis Initiative study and 697 patients who did not undergo TKA. Researchers also performed a subgroup analysis by dividing patients by their initial BMI, sex and age.

Results showed no significant difference in the average final BMI between the TKA group and non-TKA group, and no significant difference in the average change in weight over the 6-year study period. In the subgroup analysis, researchers found patients with an initial BMI of less than 25 experienced the most weight gain on average whereas patients with the highest initial BMI tended to lose weight over the course of the study. According to the results, women and patients aged between 51 and 60 years who underwent TKA experienced significantly more weight gain during the study. – by Casey Tingle

Disclosures: Kahn reports no relevant financial disclosures. Please see the full study for a list of all other researchers’ relevant financial disclosures.