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Patients with longer vertebral augmentation procedures have poorer postoperative quality of life, study finds

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CHICAGO — Among pain-related and depression-related quality of life measures, longer operative time, younger age and increased time from fracture to surgery were found to negatively impact the minimally clinically important differences seen in patients after vertebral augmentation surgery, according to results of a study presented here.

“Implications from this data include that conservative management alone would be more appropriate for patients with extensive spinal disease. Preoperative psychiatric assessment suggests depression, and earlier intervention [is needed] among patients with these fractures if possible,” Jacob A. Miller, BS, said at the American Association of Neurological Surgeons Annual Meeting.

Jacob A. Miller

Miller and colleagues conducted a study to predict the 12-month improvement in pain-related quality of life outcome measures following vertebral augmentation surgery. Overall, 143 patients who underwent either kyphoplasty or vertebroplasty at a single institution from 2010 to 2015 with prospectively collected quality of life data were included in the study. Average patient age was 71 years. The pain disability questionnaire (PDQ) instrument and EQ-5D were used to measure the patients’ pain-related quality of life.

Researchers found worse postoperative PDQ scores included operative duration, with each additional operative hour increasing postoperative PDQ scores by 7.6. They also found for each 10-year increase in patient age, postoperative PDQ scores decreased by 8.2. For each doubling of the interval from fracture to surgery, the postoperative PDQ scores increased by 3.6. Patients with osteoporosis/osteopenia showed higher postoperative PDQ scores compared to patients with metastatic lesions and history of depression. – by Kristine Houck, MA, ELS

Reference:

Jones JC, et al. Paper #630. Presented at: American Association of Neurological Surgeons Annual Meeting. April 30-May 4, 2016; Chicago.

Disclosure: Miller reports no relevant financial disclosures.